Lymphoma typically causes painless (and progressive) enlargement of one or more lymph nodes. On the other hand, tender, painful lymph nodes are generally caused by infection or inflammation.
Unfortunately, it is not possible to provide a specific diagnosis over the Internet to patients with concerns regarding enlarged lymph nodes. Therefore, you might ask your son's pediatrician if a consultation with a pediatric hematologist/onvologist would be appropriate.
Sincerely/ Robert A. Wascher, MD, FACS
www.doctorwascher.com
www.oncoguard.com