There are standardized blood and urine tests that can confirm the diagnosis of most cases of multiple myeloma. I am not sure if the "mostly normal" blood and urine tests that you mentioned included these particular tests (?). Additionally, multiple myeloma usually has a very unique and specific appearance on bone scans. So, based upon the information that you've provided, I am assuming that these tests and scans did not conclusively support the diagnosis of multiple myeloma. If, on the other hand, the radiologists who reviewed your scans strongly believe that these scans are consistent with multiple myeloma, and your medical oncologist disagrees with these two radiologists, then you should consider obtaining a second opinion from another medical oncologist.
As for the lesion in your pelvis that was seen on your PET scan, if this lesion was also observed on the CT scan portion of a CT-PET scan (or on a separate CT scan), and it appeared to be a complex cystic mass or a solid mass in your pelvis, then a pelvic ultrasound may be helpful to further characterize this mass.
Robert A. Wascher, MD, FACS
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