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Conditions and Diseases > Gout Forum > Smoking and Gout
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Q: Smoking and Gout
asked by: Makoto on September 29th, 2008
Experienced User
Anyone think there is a relationship between smoking and gout?? I suspect the amount you smoke can make your prone to smoking.
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painfree
replied on September 30th, 2008
Experienced User
I can envision a possible relationship between smoking and gout. Smoking inflames the air passage, so that the airway is narrower than it otherwise would be. That exacerbates sleep apnea, which is the repeated cessation of breathing for many seconds at a time when the airway muscles relax during sleep. The episodes of sleep apnea reduce the amount of oxygen in the blood, causing the cells to undergo a catabolic process each time which culminates irreversibly in their generation of excess uric acid fed into the blood. The lack of breathing also increases the percentage of carbon dioxide in the blood, which makes the blood more acidic so that uric acid is more readily dumped out of the blood as crystals of monosodium urate. When these crystals lodge in a joint, they cause a gout attack.
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Makoto
replied on October 1st, 2008
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I did not think of the former point, but I was considering the latter point. I feel smoking makes your blood more acidic. But the former argument in that smoking can be like sleep apnea is interesting.

Maybe it is a double wammy??
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painfree
replied on October 1st, 2008
Experienced User
It has been established by sleep physicians that smoking exacerbates sleep apnea. A rise in blood acidity can make a gout flare more likely to occur, but I have never researched whether smoking has that effect.
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Makoto
replied on October 5th, 2008
Experienced User
Quote:
Anyone think there is a relationship between smoking and gout?? I suspect the amount you smoke can make your prone to smoking.


I meant to say there might be a relationship between smoking and gout. The more you smoke the greater the more prone you are to gout attacks.

Exacerbates sleep apnea, maybe I am not sure. But even for those who do not have apnea, I think smoking can increase the amount of acidity in the blood and may help to bring on a gout attack. I do not think smoking causes gout attacks directly, but inconjuction with another factor may make gout attacks frequent/sever.
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