Hi I've had Crohns for 23 yrs with fistulas for the last 4. I tried Remicade when I first got the fistulas, it worked really well for about 5 treatments then I started to feel really unwell for days afterwards. It got to the stage that by the time I felt ok, it was nearly time to start the whole process again. About to start Humira next week. I also got leg pains but this possibly due to the doctors finding I was very aneamic as a blood transfusion stopped that pain right away.
hope any of this helps.