This is a lengthy article but I found it a useful read regarding nocturnal hypo avoidance:
http://care.diabetesjournals.org/cgi/conte
nt/full/26/1/9?maxtoshow=&HITS=10&
hits=10&RESULTFORMAT=&searchid=113
5391755635_177&FIRSTINDEX=0
It's about Type 1 diabetics but I think there are some interesting findings for everyone in there.
In my own experience, I find that although dividing meals in two throughout the day helps, if I divide my dinner I always get bad hypos in the night. Basically I need to go to bed feeling VERY full on fat and protein to sleep even moderately well. Anything that aids digestion - enzymes, stomach acid supplements, smaller portions, even vitamin C tablets - screws up my sleep. Not an ideal situation, I know.
As recommended by others, I also keep boiled eggs and almonds on hand to eat during the night, without which I can't resume sleep. And if anxiety is a problem, slow deep breathing exercises and counting or mantra-repetition always helps me, although it's taken a lot of practice to perfect it.