am 25/male. My problem is severe Premature Ejaculation. I have had this problem for a little over a year and it is ruining my marriage. I was diagnosed with A.D.D. and depression at 16, and had been on Effexor and straterra up until about a year and a half ago when I gradually took myself off them both because I could no longer afford them. I have noticed no real emotional side effects, only the PE. I donât know if this is coincidence that this problem started the same time I stopped taking medication or not. I started drinking and smoking pot when I was about 21, but completely stopped both at 23. I don't know if this problem was present during my partying phase of my life, because I would be drunk during intercourse, and had no problems with PE. But a month or 2 before I got married, almost when it felt like all the antidepressants were out of my system, this severe problem started. The feeling you get in your penis about 5 seconds before I ejaculate, is the feeling I have all day.