I have degenerative joint disease in my lower back, neck, and jaw. My doctors occasionally give me a prednisone dose pack to reduce the inflammation. In the long run, the prednisone helps, but on the second day, all my joints-especially my lower back and hips-become incredibly, almost unbearably painful. This lasts about 12 hours; then the prednisone seems to do its work and I feel much better. This has happened every time I've taken the medication and is clearly connected, yet I can't find the problem listed as a side effect. I've asked all my doctors, including specialists, and none of them have ever heard of this reaction, nor can they explain it.
I'm suffering from this as I write, and I've resolved to never take prednisone again (an obvious solution)but it's so painful that I'm concerned that this reaction is symptomatic of something other than osteoarthritis. Is there something that could be causing this reaction? It feels as if all my joints are burning like hot coals.