my daughter is 5yrs old, since last summer her platelet count has being going up. 4wks ago it had come down slightly and it was 813, this week its at an all time high of 989. she is due back to the hematologist in 3wks. but in the mean time i am really worried. all her other levels in her blood have been fine just the platelet count. can anyone tell me what this could indicate. i am doing research but most of the info is on a low platelet count
Normally, the platelet count in the blood is between 150 million and 400 million per millilitre (ml) of blood. Many factors can influence a person's platelet count, including exercise and racial origin.
In thrombocytosis, the platelet count is more than 400 million per ml.
In your daughters case, it seems probably be in the range of 813,000 - 989,000 per cmm, which is very high, and could be due to thrombocytosis.
Essential thrombocytosis is a condition where there is increased clonal production of platelets from a multipotent hematopoietic progenitor cells. ET is an uncommon disorder, with an incidence of 1â2/100,000 and a distinct female predominance, in contrast to the other chronic myeloproliferative disorders.
The condition may be a benign one, often without any symptoms or disturbances of hemostasis. In most cases, if there are signs and symptoms of circulatory overload, or bleeding or thrombotic tendencies, treatment may not be needed.
Other conditions that may present like ET, include -
1. Nonclonal benign thrombocytosis (hereditary overproduction of thrombopoietin)
2. Chronic myeloid leukaemia,
3. Polycythemia Vera, or
You may consult with your hematologist, who can do additional tests and provide you with proper information and treatment.
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