Hi I read your input on plaquenil, maybe I am just lucky, (for a change) but I have only been on it for 24 hours and my lesions that have been here 7 - 9 months, treated with everything possible, are finally improving. I can not even describe how thrilling this is as they have been horrible, open and oozing for so long. Plaquenil is the only change I have made before today. I have been diagnosed with SLE and MS since 1990s and this is the worst the lesions have ever been. Hope you are all feeling well Blessings to you all!!