Current medical treatment: He is awaiting further testing and possibly interferon treatment. Awaiting scrotal sonogram. Given incomplete rounds of antibiotics twice for epididymitis. Pain has gotten much worse. Do not know when he will be sent for sonogram in Galveston since hurricane is due there this weekend (potentially)

Your nephew needs to be examined by a doctor and not by a nurse. He has a right to that. Phenazopyridine is not an antibiotic but only a local painkiller for the urinary tract. It is usually given together with an antibiotic for urinary tract infections (UTI) but not for more than 2 days. It can be also given alone if there are no evidences of infection presence.

Phenazopyridine should be taken cautiously if the patient have a liver disorder.

The main purpose in your nephews case should be identifying the infective agent if his symptoms are caused by a UTI or genital infection. There is no logic to taking a potentially dangerous medicine (because of Hepatitis C) without treating the possible uro-genital infection with a proper antibiotic.