Pregnancy Q and A Forum - PCOS, Metformin and Pregnancy

Pregnancy Forum > Pregnancy Q and A Forum > PCOS, Metformin and Pregnancy

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Q: PCOS, Metformin and Pregnancy

asked by: pregwith2 on June 24th, 2009

New User

Hi,

I have PCOS and delivered a healthy son last year in March.

I went off metformin to breastfeed, and suffered 3 miscarriages within 10 months of my son being born.

I recently started my 2000mg dose of Metformin again, only to find out I am pregnant.

It seems I started it about 1 week after we conceived - I am worried that because I wasn't on Metformin before ovulation, my miscarriage rate is going to remain the 60% it is for untreated PCOS.

Could you please advise whether my risk is lowered if I am on it now (5 weeks 2 days) since approx/ 1 week after ovulation?

Thanks in advance

Replies(2)

sjkoepke1

replied on June 24th, 2009

New User

I think you will be ok. My friend has pcos and took metformin for a long time. she was told she didn't ovulate while she was taking it so she quit, and found out she was pregnant 2 weeks later. she did have 1 miscarriages and then she got pregnant with a healthy son. all without the metphormin. I think you will be alright. just don't sweat it ok! Good luck!

MandMs

replied on June 26th, 2009

Extremely eHealthy

The current recommendation for a patient who has conceived on metformin, is to discontinue the medication once pregnancy is confirmed.
Indeed, there is some data about use of metformin and decreased percent of miscarriages and birth defects in women with PCOS, but, these result come from small studies and they warrant additional experiments to be confirmed.
As any other medication, it is better not to be used during pregnancy.

For correct answer, consult your fertility clinic!
Best wishes!
Marija

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