I don't think you're being paranoid at all. I would take her to the eye doctor ASAP! Retinoblastoma is a cancer, afterall, and can spread spread outside of the eye or to other parts of the body.

I agree with the previous poster. The photos do look convincing to me for retinoblastoma has you said that it has occured in many photos. Consult a doctor, quickly!

As a teacher of students with visual impairments, I have had experience with students that have retinalblastoma....you need to see a doctor immediately! If not the emergency room today, then your pediatrician on Monday. The size, location and consistency of that reflection are absolutely signs of a tumor. This can be life threatening. Please please please do not ignore this or take it lightly. For your child's vision and possiby her life...get to a doctor.

We went to the pediatrician and the ophthalmologist. They still have not figured out why but she does have 20/200 vision in that eye. I can't believe I never noticed she can't see out of one eye.

Daisy, I'm glad to hear that it's not retinoblastoma. It's a good thing, though, that you caught the vision defect as soon as you did. She could have lost all vision in that eye if you hadn't acted so quickly.
Did your ophthalmologist mention Coats' Disease or blond fundus?
Coats' disease is also known as Coats' Retinitis, Coats' Syndrome, Exudative Retinitis, and Retinal Telangiectasis. Coats’ disease is a very rare condition where there is abnormal development in the blood vessels behind the retina. The blood rich retinal capillaries break open, leaking the serum portion of the blood into the back of eye. The leakage causes the retina to swell, and can cause partial or complete detachment of the retina. Coats' disease is seen predominantly in males, about 69 percent of the cases. It progresses gradually and affects central vision. It is almost always unilateral (affects only one eye). If caught early, some level of vision can typically be restored. If not caught until it's late stages, complete loss of vision can occur. In it's final stages, enucleation (removal of the affected eye) is a potential outcome.
Blond fundus, also called ocular albinism usually affect patients with little pigment, usually white-blond, blued people. I can't tell what color her eyes are from your pictures. Are they brown? The sites I visited used so much medical language it was hard to understand the cause but I think I got the gist of it: if you and/or your husband carry the gene for albinism it can cause IA in any children you produce.
I hope you find an answer soon.

I found two other possibilities: pediatric cataracts or ROP, Retinopathy of Prematurity, a disorder exclusive to premature babies.

I see that this is an old post, but wanted to put in my two cents as other parents may come across this page later as I did. I was seeing the same white-eye reflection in pictures of my four year old son. Of course, I panicked after reading all over the internet about retinoblastoma. We saw an opthamologist today, and fortunately he does NOT have it. I learned that it is often diagnosed around age 1 (rarely as late as 3 or 4) and that this cancer is quite rare. They believe my son has strabismus (much more common), which is when the eyes are not in perfect alignment. The slight misalignment can cause one eye to reflect white, as the flash is hitting the edge of the retina which has less pigment. The misalignment is absolutely NOT noticable but after giving him some impromptu eye tests at home, we learned he has poor vision in one eye (the one that is reflecting white). Anyway, definitely see a doctor ASAP, but don't jump to the worst conclusion right off the bat.