We have completed chemo which got rid of most sores. Then went to Targretin which finished one more. The worst one was treated with radiation. The targretin caused flakey skin - so bad that we sweep up pan fulls of skin flakes every day. After he couldn't stand that medication any longer. We stopped, the symptoms have not gone away after 3 months. Skin is still flaking and he is very cold all the time. We really would like to talk to someone who has gone through this or knows of someone who has. Doctor's don't know what is going on.