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Q: MS induced neuropathy
asked by: DoctorQuestion on December 11th, 2008
Approx 6 weeks ago both great toes became cold and sometimes painful and since then has come and gone except for today. All toes are involved minus little toes, I am wearing 3 pr of socks with no relief and now both feet are wrapped in a heating pad for the past 30 minutes on high, toes are still freezing however my feet are sweating.

I recently had blood sugar test and it came back normal, dx'd with hypoglycemia years ago. My toes are not blue like one would find with Raynalds Syndrome and my neuroloigst confirmed this today.

Could my cold toes be a huge red flag that this could be diabetes related? I have one parent who is hypoglycemic and his mother and a few of his siblings are diabetic.

Also is there a suggestion on how to get this coldness to go away?


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Dr. Goce Aleksovski , MD
replied on December 12th, 2008
Diabetes Answer A5083
Current medical status: Started 6 weeks ago, both great toes were cold then went away only to return and has migrated to other toes except for little toes, thus far. Intensity has increased and is becoming painful.
Current medical treatment: Saw my neurologist today for a routine exam for MS and he examined both feet and toes and states toes are definately cold, not blue with great pulse, etc. 3 weeks ago had my yearly physical and blood sugar came back normal.


Given the symptoms you provided (multiple sclerosis, cold toes, not blue), you might experiencing neuropathy due to the damage multiple sclerosis causes to certain nerves. One of the complications of multiple sclerosis is actually damaging nerves. In this case, multiple sclerosis might have damaged the nerves that affect the small blood vessels that supply the toes with blood.


The cold toes can also be caused by diabetes, but your laboratory tests do not show hyperglycemia.




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