Reversible hyperactivity, agitation, anxiety, insomnia, confusion, convulsions, behavioral changes, and/or dizziness are some side effects due to brain reaction to this drug (not an allergic ones).
When treating chronic urinary infection, the dosage can't be lower than recommended (sometimes, it can be prescribed as higher dose than the regular one) In stubborn infections, therapy may be required for several weeks.
Clinical and/or bacteriological evaluation before therapy and follow-up for several months after cessation of therapy are often necessary.