I feel like I have a lump in my throat/neck and right chest tightness which usually appears or worsens after eating food. It feels like someone is pushing on the spot/indention where my neck meets my chest. I often feel winded and have a hard time talking or reading to my kids. It's always better in the morning and worsens throughout the day. It comes and goes throughout the day, and some days are better than others. I also have an undiagnosed condition which I am treating with Prednisone, but I'm not sure if all of this is related or not. My undiagnosed condition involves the above symptoms plus severe edema (esp. in face/eyelids and lower extremeties), itching/rashing on legs, hair shedding, bulging eyes. I've had lots of labs, scans, & a bone marrow biopsy. I have/have had low complement (C3, C4, CH50), low IgA, high eosinophils, low B12, and low iron stores (shown in BM biopsy). Any help you can offer would be wonderful. I do wonder if the throat/chest tightness could be anxiety?