Lucrin depot is a GnRH-analog that, if given continuously, suppresses production of FSH and LH and then indirectly suppresses estrogen and progesterone production from the ovaries.


Lucrin shuts down the axis hypothalamus-pituitary-ovaries and prevents further ovulations and periods. Now you experience irregular uterine bleeding (metrorrhagia) because the level of estrogen hormones increases shortly and then decreases completely. This is a temporary condition that can last until estrogens reach zero level and endometrial growth becomes completely suppressed.


This procedure is used for treating endometriosis. You might have endometriosis of the removed ovary because a chocolate cyst is caused by ovarian endometriosis.


This procedure with Lucrin is also used to prepare the woman for “in vitro”-fertilization. A woman’s own production of FSH and LH should be stopped before starting stimulation with synthetic FSH and LH from outside.


You should consult your gynecologist about these side effects from Lucrin.