Adequate oxygen should be given to relieve hypoxia. A belief (ingrained from medical school) is held widely that too much oxygen causes significant respiratory depression. Multiple studies in the literature dispute this view. With administration of oxygen, PO2 and PCO2 rise but not in proportion to the very minor changes in respiratory drive.
Attacks of COPD are not provoked by oxygen therapy but usually by some infection.
Weight loss can happen in some cases of COPD, usually in those with emphysema.

I was diagnosed with COPD last year. It was then determined that the materials in Orthotics and Prosthetics I have been exposed for the past twenty five years have damaged my lungs and perhaps other systems. As I was a smoker up to ten months ago, properly diagnosing my problems apart from that is difficult at best. In conjunction, the materials and field of Prosthetics and Orthotics is young and not well known and thus the materials and adverse effects of MEK and other nasty items not well known by the medical community. Are cysts on the lungs common? Are breathing tests that are not awful go along with three episodes of pneumonia and the inability to work and speak for very long periods of time coincide somehow? Answers and relief from suffering would be so appreciated.