The first thing that comes to mind is a type of psoriasis however the area is ususally red. Go see a dermatologist. It may be a staph infection or some other type of infection. Proper treatment should be given.

How many pimples? I had that happen to me also only it was just a few, but always on my hands. I wash my hands alot and was usually washing with dishwashing soap. When I stopped using that and switched to a more gentle hand soap I stopped getting the pimples and haven't had it happen in years.

This probably does not relate to you, but I have mitral valve prolapse, and that is one of the symptoms. I am sure it is just psoriasis, or a condition similiar to that and will go away in time. Mine are TINY red bumps, no pus, just kind of fluid filled that come and go. Are you on any kind of medication, that could also be causing the problems. Try using antibacterial lotions - that could help the condition.

i get the same thing every summer, then it goes away in the winter......as long as i can remember, still don't know what it is, but yeah, on my right index on the side where the main joint is and sometimes down my my knuckle but always on the side, and it goes to the side of my thumb that touches the affected area on my index....weird..sorry i don't have an answer but I can relate..

I get the same thing. Clear blisters on my hands that don't bother me at all other than just being there. Sometimes I get larger ones on the bottom of my feet, and they are annoying.

Only in the summertime, when it gets warm, for the past four years or so. I think it's an allergy. I've been to the dermatologist and she thought the same.