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Q: Lisinopril & mood changes
asked by: M5ward on May 6th, 2008
New User
My son (35) was put on Lisinopril a few months back. Along with the "normal" side effects (cough, tiredness, etc.) he seemed to experience a change in disposition. He angered easily and flipped out a lot. He stopped taking it (I know he should have consulted his doctor, but he didn't) and his disposition returned to normal. He recently started taking it again thinking the mood changes weren't due to the medication, but now he is reverting to the easily angered, flip-out person he was the first time. Has anyone else experienced this sort of reaction with Lisinopril?
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Marianne0558
replied on May 6th, 2008
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This was in our yeseterday newspaper.....
"The girlfriend of Russell Daniel Andrew Breaker,who's accused of gunning down a man in a West Ashley condominium Sunday, said he had a dramatic personality change after doctors altered medication he takes for his heart and blood pressure.

Breaker, 22, allegedly fled the Concord West of the Ashley complex about 6:45 a.m. after shooting Michael Brock, 29, three times, according to police reports.

Elizabeth Payseur, 19, said she grew up with Breaker in West Ashley and has been going out with him for more than four years. The couple lived together in an apartment on Carriage Lane and have a child together, she said.

Breaker's behavior had grown more controlling, violent and unpredictable since doctors altered his medication about a month ago, she said. He also began drinking heavily at that time, she said.

His behavior change was surprising, she said. "He was not like this," she said. "He's not a mean, physically violent person. It's not in his nature."

But over the past few weeks, she said, as Breaker became more unstable, she began spending some nights at her mother's condominium because she was afraid of him.

Payseur said her 2-year-old daughter was at her mother's home in Hollywood at the time of the shooting.

Payseur said she had spent Friday night and most of the day Saturday with Breaker. They were arguing when she went to work at Jersey Mike's on Sycamore Avenue in West Ashley at 4:30 p.m., she said. And he called her at work and continued arguing, she said.

Brock was her friend and co-worker, she said. He came home with her because she told him she didn't feel safe.

Brock went out on the third-floor unit's balcony to smoke about 6:45 a.m., she said. Soon afterward, Breaker kicked the door in and hit her in the face, according to the police report. Then he walked onto the balcony and shot Brock three times, she told police. "Michael didn't say one word," she said.

Payseur said she's staying with family members out of state until law enforcement officers find Breaker.

Greg Whitehair, who hired Breaker a few months ago to do odd jobs, said he's also shocked by the allegations.

Breaker never missed work, Whitehair said. "He never even said a cuss word on the job."

But then Breaker didn't come to work last Wednesday, he said. And Whitehair never heard from him again.

Addah Carrigg,29, said Monday that she had been going out with Brock for the past 10 years. Brock, she said, was a loving father and an "all-around great guy."

It is definitely possible to have mood-alterations if medications are changed. Obviously this individual had this problem as well.
You should probably encourage him to go back to the doctor before something tragic like this happens.
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Anmos4
replied on July 3rd, 2009
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I know personality changes can occur when someone begins taking Lisinopril. My husband's insurance changed and so too did his coverage for a blood pressure medicine he had taken for sometime. His insurance would pay for Lisinopril which he took for sometime until he collapsed in a neighbor's yard from a combination of no hydration from being in the sun all day and taking Lisinopril. I had recently determined due to his temperament that he was developing dementia and/or heart disease. After tests disclosed no other problems, he discontinued Lisinopril for a month on the advice of a cardiologist and resumed a much lower dose of Lisinopril a month later based on a daily log he kept of his blood pressure for a month. During the month hiatus, his personality drastically improved. Upon resuming Lisinopril he returned to his angry, hostile, hair trigger temper. His response time was slow to questions and situations. I KNOW the Lisinopril was exacerbating some personality tendencies he already had but kept in check normally. Even his doctor could detect the hostility and said he was having an allergic reaction to the Lisinopril. He is now trying another blood pressure medicine (Beta Blocker).
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