I have never been diagnosed with either gout or lactic acidosis. On the other hand, I have not seen a doctor for the past 12 years.
Here are my symptoms:
-Heavy sweating,
-Burning sweat on the skin
-Urine turning dark at the slightest effort
-Progressive joint pain started 12 years ago with the 2 toes and toe muscle rigidity. Currently most joints hurt on a permanent basis, the best is discomfort, the worst after a bit of "work" of effort is major pain, stiffness, cramps in the feet, calf, back thigh, the back at the lower back, around the kidneys and the shoulder blade, and rarely the hands.
Spells of light headedness, episodes of fainting
-kidney discomfort as if two thumbs were continuously pushing on each kidney at best or when at worst, were pinching them
-whole body itching (this happened 10 days ago, only once, lasted 3 of 4 hours, heavy progressive itching similar to athletes foot but with not visible mark on the skin, the feet, the palms, the ears itch particularly, but also the groin area, the calves, the thighs, the side of the upper body.
Outside of the itching, all the other symptoms have been getting progressively worst for the past 12 years.
The itching incident was preceded by almost fainting 3 times in 2 days, shortness of breath, fatigue, headache, etc...
There is no blood in my urine or feces; I have no signs of jaundice.
I drink 6 quarts to 12 quarts of water a day depending on how much I have sweated.
I had a form of non-viral hepatitis when I was 21 years old, some 30 years ago. I think they called it biliary hepatitis (the doctor think I got monoxide poisoning for bad exhaust from the natural gas heating ducks in my apartment). I never had surgery, have spells of allergies to pollen, I had a displaced or enlarge oesophagus that created an ulcer in the early 1990's, it completely healed in a few months. I am currently 220lbs, 6'2". I had all through my life episodic spells of stomach burns but this has almost completely subsided for at least 10 years.
All my life I have had a volatile body weight, from 160lbs to 260lbs; but for the past 10 years I have been more stable between 200 and 225 lbs. I am 51 years old.
I over did it on fructose for about ten years drinking up to a quart and a half a day of orange or apple juice in the 1990's and 2000's. Same with soft drinks which I over consumed from 2000 to 2011 up to 1 quart a day. I progressively stopped colas and soft drinks from march 2011 and completely stopped fizzy drinks last October. This helped temporarilly my muscle stiffness, but the pain has come back. I only drink about maximum 10 ounce of fructose base juices a day now. I have had all my life urges for sugar or starches (starches more than sugar). I was never diagnosed with a glycemic condition but never tested either.
Now because I got worried, I started to read about all this 10 days ago. I noticed that some of my symptoms were similar to gout. I once thought that the pain in my joints could have from Lyme disease because I live in an area prone to it and thought I might have gone bitten; it is a rural area, and I walk my dogs in the fields where they often get tick bites, ticks that I have to remove. Not all of them are black ticks but some are. They get vaccinated against Lyme disease.
On your forum, I read that non-effervescent baking soda could relieve the pain due to gout crisis. I started last Wednesday June 13, with 1 (one) teaspoon twice a day and everything changed. My urine is stable in color, the pain is gone in my joints, I feel energized, but there is still what I would call small discomfort but not pain in the joints. The constant feeling of pressure or pinching on my kidneys is gone. My sweat dose not burn anymore, but on the other hand yesterday while I was working outside, my arms and forearms became full of blisters that did not really burn but they looked like blisters from burns. The blisters subsided after an hour or so. But I now believe I may have lactic acidosis that probably created gout symptoms and hypereuricimea; which is often the case when we have a predisposition for gout.
Last night, because I am worried of the excessive sodium intake, I lowered my dosage to half a teaspoon, and already my symptoms are coming back.
I ordered some Pepcid Complete from the pharmacy to see if the sodium carbonate could be alternated with the sodium bicarbonate so that I would not overdose on salt.
They are other details I left out, but I think it should be enough for now. Something a bit more detailled than just go see a doctor. Last time I got my blood analyzed, they came out with reults that were not my blood group. Get the idea!
If a doctor can orient me into what I should do, it would be great, but sadly, for political reasons, I cannot use the canadian (In fact the quebec) medical services.
Canadians have never had my health at heart.
Thank you very much.
Denys Picard
Dual citizen (Canada and USA) residing in Canada
Please apologize the spelling mistakes, they are anatomical terms I am never sure about the spelling and did not want to take hours checking all of them, my mother tongue is French, as you have probably figured out.
Update June 19 2012:
I would like to offer a bit more details since no one has contributed a commentary yet.
Things I believe we can put aside as theories: I don’t believe I have a form of cancer. While lactic acidosis is often associated with cancer patient whether the disease has induced it or the treatment, I have no known history of cancer in both sides of my family tree. I know that whole body itching is one of a rare precursor signs or alarm signs of pancreatic cancer, it is the sign that the bill is not secreted because ducks of the gall-bladder are jammed and bile does not circulate. I am sure in my case there can be another explanation.
I also know that I do not have AIDS; AIDS patient often develop lactic acidosis. (I know that some communities are always angry when we affirm we don’t have AIDS, but that is it. I want to make sure that no one starts false rumors on my potential health circumstances. As I said, I have no official diagnosis because I have not seen a doctor in 12 years).
Now, even if I don’t have pancreatic cancer, I may have either liver, pancreatic or kidney disorders that may be responsible for the acidosis. Or it may be enzyme mutations or bacteria, they are about 6 well known mutations or (lack of/excess of) of enzymes that create lactic acidosis, most of them have to do with the Kreb cycle ( therefore production of ATP); these are fructose, lactate, carboxylase enzymes, etc. It could simply be lack of oxygen in the mitochondria. Now that I have looked at the symptoms, I can see that I have both signs of excessive lactic acid and insufficient ATP all my life, but obviously, the last 7 years have seen it progress dramatically.
As for gout, I am quite sure it was produced by the excess lactic acid. The latest scientific works on gout are starting to identify the mutations of certain enzymes that would be responsible for the crystal deposits. The enzyme suddenly decides to get rid of the excess serum uric acid levels by deposing them in the joints. Those that have that mutated gene develop gout, therefore you need a propensity to develop gout, and it is not simply the elevated acid level.
As for the pain, I am more confident now that these are not created by the uric acid, but by high levels of histamines. Histamine is created by lactic acid. Excess lactic acid levels mean excess histamine levels, means excessive pain. Sodium bicarbonate inhibits lactic acid, therefore reduces the amount of histamines in the body. Sodium bicarbonate is given intravenously to some patients that have AIDS or cancer. That is why people how take allopurinol don’t see the pain go away (allopurinol only lowers uric acid levels), and why some rheumatologists prescribe Sodium carbonate to patient using allopurinol so the pain can be alleviated. I also believe that gout crisis have less to do with deposits in the joints than in the tissues surrounding the joints, that is when the histamines create great pain (but I am not a doctor, nor a scientist, so this has no authority safe for a “feeling”).
Important to differentiate between “treatments” as the scientific world uses it -curing a condition—and the way most people use it. It must be clear that sodium bicarbonate can alleviate the pain by reducing the level of lactic acid in the tissues and the body, but it does not cure acidosis or gout conditions.
But from my readings I can sure affirm that overdose of fructose is not recommended for gout patiens, and low purine diets may affect B12 vitamin levels dangerously; which is essential in the ATP cycle. Low ATP, more lactic acid as a by-product, more histamine, more pain…
Recommended reading: Recent insights in the pathogenesis of hyperuricaemia and gout; (2009) Philip L. Riches, Alan F. Wright and Stuart H. Ralston
Rheumatic Diseases Unit and 2MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK
That is it for this morning,
Denys icard,
Proud to not have a Facebook acount and I never will have one (I say this because people have open fraudulent Facebook accounts using my name, facebook garbage land)
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