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Conditions and Diseases > Liver Disorders, Hepatitis A,B,C Forum > Isotane , damaged liver , and liver enzymes
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Q: Isotane , damaged liver , and liver enzymes
asked by: DoctorQuestion on June 10th, 2008
I am so worried now. My questions are: 1. why does my SGPT increase even though I already stopped isotane? This is my 4th month of liver rest.
2. Is it okay to have workout for people with fatty liver? I am analyzing my situation, my SGPT is increased so that means my liver is inflammed. Is it not okay if I am having a gym workout? Some exercise require abdominal compression like sit ups. Pls correct me if I am having confusion.
3. Is it okay for me to take Mega mass 4000-a supplement for people having workout. Will my liver be damaged further if I take?

Thank you in advance! I look for an immediate reply..I am really worried.. :(


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Dr. Nikola Gjuzelov , MD
replied on June 11th, 2008
Liver Disorders, Hepatitis A,B,C Answer A4257
Raised liver enzymes (SGOT and SGPT), increased blood fats, and fatty liver are common side effects from Isotane (isotretinoin). Therapy with Isotane usually lasts for 4-6 months. Therapeutic effects can be present even after stopping the treatment but, unfortunately, the same stands for the side effects too.


I think that people with a damaged liver (raised enzymes and fatty liver) should not have an excessive workout. They should also avoid amino acids and protein supplements like “Mega mass 4000” because high protein intake stresses the liver.


You should have regular check-ups of the liver enzymes completed.





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