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invaisive trophoblast antigen found in 18 mos old....

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March 13th, 2012
my 18 month old daughter, recently had a blood test, the doctor called to say that a low level of (ita) was found, i dont understand what this means, my next app is not for a couple of weeks, feeling very confused, as it wasnt explained to me, any info would be great. many thanks.
worried mum.
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replied March 28th, 2012
Welcome to e health forum.

Invasive trophoblastic antigen, ITA is a hyperglycosylated form of hCG that is produced by cytotrophoblasts during embryonic implantation and trophoblast invasion of the uterine wall. Prenatal Screening for conditions like Down's syndrome and neural tube defects is done by testing the mother's blood samples for markers including ITA, Alfa feto protine (AFP), dimeric inhibin A (DIA), unconjugated estriol (uE3), etc.

In addition, ITA or HCG is also a tumor marker in gestational trophoblastic diseases, like hydatidiform mole, choriocarcinoma, etc, which are seen during pregancy.

High Serum HCG levels in pediatric blood samples - can be indicators of hepatoblastoma, hepatocellular cancer and infantile liver choriocarcinoma and germ cell tumors.

The low levels of ITA, seen in your daughter, are not of any significance.

You may consult with your doctor, who can provide more information and proper advice.



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