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Information about germ cell aplasia

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I need to know whether sperm production is possible even though under testis biopsy of left testicle i have germ cell aplasia as TB of right is not done. Also, how long i need to wait after varicocle repair for sperm to come from my semen. can i go for icsi after 3 months of my varicocle repair and what is the chances of pregnency for my spouse.


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replied February 2nd, 2010
Infertility Answer A9709
Hello,

Welcome to the ehealthforum and I am really glad to help you out. Germ cell aplasia means that the semen lacks the germ cells which lead to the creation of sperm and is azoospermic (devoid of sperm cells). In most of the cases, male fertility is impossible. If a testicular biopsy reveals that there is a small amount of sperm present in patches of the testes, a specialist can extract them for in vitro fertilization (IVF) or artificial insemination.

As per quoted in emedicine, following varicocelectomy, approximately 66-70 percent of patients have improved bulk semen parameters, and 40-60 percent of patients have increased conception rates. Because human spermatogenesis takes approximately 72 days, the first improvements in semen analysis results are typically not apparent until 3-4 months after surgery. With ICSI, surgeons inject a single spermatozoon into an oocyte to initiate fertilization and, eventually, a pregnancy. You have to discuss this in detail with your fertility expert because ICSI is not without side effects and risks.

It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For an exact diagnosis, you are requested to consult your doctor. I sincerely hope that helps. Take care.






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