Chronic diarrhea can be due to malabsorption syndrome. Malabsorption can be due to many reasons including certain liver disorders. It is true that increased levels of the enzyme alkaline phosphatase can be due either to a liver disorder or bone disorder. That’s why your son needs several more tests (AST, ALT, gamma-GT, bilirubin…) to check his liver condition. If everything is okay with the liver, tests can be focused on the bone metabolism. Malabsorption can’t cause a liver disorder but can cause a disturbance in the bone development by providing insufficient calcium, phosphates, and Vitamin D. This means that the serum levels of calcium, phosphates, parathormone, calcitonin and Vitamin D should also be checked.
This means that all 3 possibilities (malabsorption, liver disorder, and bone disorder) can be present at the same time and even be connected.
You may want to consult a pediatric gastroenterologist about this.
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