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I need to still the paranoia...

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Dear Dr. Anvekar,

I had a sexual encounter about 50 days ago in Germany with a prostitute, who started performing oral sex on me without a condom. I did not realize it at first, but when I did after two minutes or so I stopped her. Thereafter I put a condom on and proceeded to have intercourse.

Since then I have however become paranoid ... read a lot on the internet... I have returned to Delhi, India yesterday and intend to give a sample for a HIV DNA PCR at a SRL center tomorrow. My question to you is, is the HIV DNA PCR test also senstive after 50 days ie. any good?? Of course I will have an antibody test done as soon as 3 months are over ... but I need to still the paranoia fist and therefore decided on the PCR test... Looking forward to your response... Arjun


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replied January 29th, 2012
HIV and AIDS Answer A30902
Hello and welcome to e health forum.

Since the intercourse was protected, it might not be enough to pass on the infection. With respect to oral sex, transmission from a female to a male during oral sex is very less. There have been recorded cases of getting HIV from sucking or giving head BUT ‎there have been no recorded cases of getting HIV from getting sucked.‎ Hence the overall risk of infection would be less.

But it is always better to get tested, so that concrete evidence of a HIV negative status will help to reduce the anxiety and stress.

Polymerase chain reaction (PCR) for proviral DNA (PCR -DNA) is a important test that can detect ‎‎‎‎proviral DNA during window ‎period, can ‎differentiate latent HIV infection from active viral transcription ‎‎‎‎and can quantitate the ‎number of HIV DNA. ‎

The DNA PCR is the absolute most sensitive test for HIV, and can be done anytime after 2 weeks post exposure. In case it is Negative, it will be definitive that you do not have HIV infection.

HIV DUO test, which is also called as a 4th generation HIV test, is a 100% ‎sensitive test, and it tests for both HIV-1/2 antibody and p24 antigens. Its specificity is 99.77% in individuals ‎at low risk for HIV infection. Hence it is a very accurate test for HIV screening. ‎This test can be done at any time after 4 weeks of exposure, and will give a very accurate and reliable reading to confirm your HIV status.

Since it is already more than 7 weeks (48 days) since the exposure, it will be much economical for you to undergo a 4th generation HIV test, instead of a PCR test (which is expensive). There is no need to do a expensive test, in your case, since a very reliable test, like HIV duo test is available to know the same.

I hope this helps.‎


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