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How accurate is a HIV DNA (PCR)test at 9 days and at 14 days

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Thank you Dr. Anvekar for your previous response.
Can you tell me How accurate is a HIV DNA (PCR)test at 9 days and at 14 days?
I have seen stated on here that they are accurate and conclusive at those days? Of course the 14 day being more accurate.


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replied February 29th, 2012
HIV and AIDS Answer A32178
Hello and welcome to e health forum.

Please mention, the mode of your exposure, so that I can advice you on your actual risk of contracting HIV.

HIV-1 Proviral DNA testing is indicated for testing infants born to HIV-positive mothers, resolving indeterminate western blot results, and for detecting early HIV infections in high risk cases.

In cases of high risk cases, the HIV DNA test can detect HIV DNA in the samples within 7 to 10 days. But studies indicate that upto 90% cases can be detected within 2 weeks post exposure. In rest of the cases it may take upto 3 weeks.

Hence a median period of 2 weeks is best advised for low risk individuals seeking early diagnosis.

Since you have already done the test at the 9th day, there is no need to do the test again at 14th day, as it would not change significantly in a few days.

Instead, you should wait till the end of 4 weeks and do the 4th generation HIV test.

In case, your risk of infection is low (as determined by your counselor or doctor), and the 4th generation HIV test is negative at 4 weeks, then there would be no need to do any further tests.


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