I have been on it (60 mg) for migraines and persistant daily headaches and it is working but I had to go with a tapered up dose. I started out on 60 mg and it was too much. Then the neuro doc had me take 30 mg for a couple weeks and then 30 in the AM and 30 in the afternoon.

Cymbalta has some powerful side effets and getting off of it is rough from what I have read. I have not had any weight gain yet but I do get carb cravings so I am watching out for weight gain. Now that my migraines are under control I am much more active so maybe I am burning them off as fast as I am eating them.

The side effects I am dealing with are persistant ringing in the ears, painful and frequent urination, intense/bizzare dreams, overheating/sweating, not able to concentrate, low sex drive and un-syncronized orgasms.

But after going through multiple migraine meds Cymbalta is working but I am not sure how long I can keep dealing with the intense side effects. Just the ringing in my ears is going to drive me insane real soon. I try to keep my environment as noisy as possible to drown it out.

If there is any other med that may work I would try it first over Cymbalta. It's a double edged sword.