Diabetes Forum - Glyburide and Metformin HCL

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Q: Glyburide and Metformin HCL

asked by: tko4irish on April 13th, 2009

New User

I am an insurance agent trying to educate myself regarding Diabetes. I have a client who was just diagnosed with Diabetes 2 a week or two back. Approximately how long should it take for his Glyburide (2.5mg 2x daily) and Metformin HCL (500mg 2x daily) to start 1.) start his blood sugar levels to improve, and 2.) reach their therapeutic max level? He is age 84, slim build, non-smoker, non-drinker, and otherwise good health and very active. I know this will not be a precise timeframe and that he will need to follow Dr's orders re: blood lab work, etc. Please advise, thanks!

Replies(1)

Dr. Joel W. Steelman , MD

replied on October 21st, 2009

Type 2 diabetics have different responses to medications from one person to another person. Response to a medication such as glyburide typically is seen within a week of reaching a therapeutic dose - the level of this dose differs based on a lot of factors. Metformin has a same sort of pattern.

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