Genital Ulcer Disease is usually caused by sexually transmitted disease like genital herpes, syphilis, Treponema pallidum infection etc. The ulcers in Genital Ulcer Disease are like lesions affecting the surface of the skin. They can vary in depth, and might even reach the subcutaneous blood vessels thus causing bleeding. Since the ulcers are most similar to wounds, they are painful. They can heal completely if the primary cause for the ulcers is treated. After the infection is treated it might take several weeks for the ulcers to close completely. The tissue that will cover the ulcers might be connective tissue instead of skin, thus causing scars. Genital ulcers are not common for HIV infection, but can appear in weakened immune system due to increased possibility for other infections to occur.