Genetic disorder? Relatives over 7' tall?

Do your sons exhibit any of these problems as well?
-nearsightedness
-sunken in chest(funnel chest) or a chest that sticks out (pigeon chest)
-flat feet
-joints that are unstable or overly flexible
-thin, narrow face
-extremely long fingers, toes, arms and legs
-overcrowded mouth and high arched palate (roof of mouth)

Now as far as your father and his brother go: Did either of them die young (under 50 years of age)?
Was the cause of their death due to aortic dissection or a tear in the aortic arch?

I believe that your children should be checked Marfan Syndrome, a genetic connective tissue disorder. I don't have Marfan Syndrome and I am not a doctor, but I do have a connective tissue disorder related to Marfan Syndrome (Ehlers-Danlos), so I do have limited knowledge on Marfan due to the work-ups performed on me.

Untreated, Marfan Syndrome can be fatal. Aortic tears and dissections are one of the results of having Marfan Syndrome. Not everyone with Marfan Syndrome gets an aortic tear/dissection, but regular heart monitoring MUST be done to ensure that any signs of a potential tear/dissection can be caught early.

I advise you to take your sons to the family doctor if they have most of the signs of Marfan Syndrome. Your family doctor will be able to refer you to a geneticist who can perform the necessary genetic screening to detect the genes for Marfan Syndrome.

Best of luck to you and your children and I hope I have helped in some way.

For more information on Marfan Syndrome, please visit this site: http://www.marfan.org/marfan/