Join Our Community!
Share
Cancer > Thyroid Cancer Forum > FNB shows 1.5 cm isthmus hurthel cell neoplasm
Avatar
Q: FNB shows 1.5 cm isthmus hurthel cell neoplasm
asked by: marty217 on October 5th, 2009
New User
8 moths ago thyroid nodule found by dopler of neck. Just tool ultra sound and found a single 1.5cm or 15mm nodule in right isthmus extending slightly into right superior loeb with high fluid level and NO vascularity no califications or lymphadenophy I am 58 years old

fine needle biospy showed isthmus hurthle cell neoplasm with 1differential diagnosis included hurthle cell adeoma. or carcinoma or less likly hyperplasia. The smears were cellular, numerous microfollicles composed of exclusively hurthle cells with prominent nucleoil, occassional groves. and pleomorphism and finally rare psammoma with scanty colloid in bloody background. I was told to have isthmus and right loeb removes to see if it is cancer. Have no symptoms and no lump. TSH was 2.0 and blood test normal.I will see surgeon in 2 weeks and had fnb smears sent to him

what is this neoplasm. is it considered cancer or a just a growth and whatis the rate of growtth. I dont want rai so can i have external beam instead of rai as rai does not do well with rai can I just skip rai altoghter to avoid permanent radiation effects? Can also I have this new thyroben injection instead of going off thyroid medication. Is 2nd nneedle biospy waste of time. I dont want radiation.

I am going on vacation end october, get 2nd opinion and take a 2nd biospy. I woild like to monitor 2-3 months and any growth get immediate surgery

please givw me your advise
Did you find this post useful?
|
Replies(3)
Avatar
MyrahU
replied on October 6th, 2009
Active User, very eHealthy
I'm not a doctor, but my diagnosis was very similar to yours--single nodule, Hurthle cells shown on FNA biopsy, but they weren't able to tell me for sure it was cancer until I had it taken out and they looked at the entire nodule. I had the second half of my thyroid removed a month later, had radioactive iodine treatment, and have been cancer-free for three years. I was 24 years old. All my blood tests were totally normal, too.

You said you have a nodule but no lump? Isn't the nodule the lump?

It is up to you and your doctor whether it is necessary to have surgery now or if you can wait the two or three months. If it is slow-growing, that may not be enough time to see if it gets bigger. If the doctor sees that you may be at higher risk, two or three months may be too long to wait.

Also, please don't confuse RAI treatment with "radiation" that they give for other cancers. They are very very different. The RAI is a single pill that targets any remaining thyroid cells in your body. An external beam will not work. Yes, you have to stay away from other people (and animals) for two to four days to avoid damaging their thyroids (not because you will give them radiation poisoning), but after that, you're fine. No hair loss. Yes, you may get nauseated for a few hours if you are prone to it, but it passes after that. Any pain in your salivary glands can be prevented by sucking on sour candy. People have been given this treatment for thyroid cancer for more than 50 years and the long-term side-effects are very low, especially compared to the risk of not having it done at all. I went through it and compared to what other cancer patients have to go through with radiation and chemotherapy, this was a walk in the park. Even with the low-iodine diet.

You and your doctor will have to decide if the Thyrogen injections are an acceptable alternative to going off your thyroid medication. They mainly use the injection for scans, not for ablation. If you can't use them this time, you can use the injections for follow-up testing.

Only your doctor can tell you if a second biopsy would be a waste of time, but personally, I think it probably would be. No matter what it said, it wouldn't really change things because of the rates of false-negative and false-positive results. If they don't find Hurtle cells next time, that doesn't mean they weren't there, it probably means that they missed them the second time.

Call your doctor and see if you can wait for surgery until after your vacation or even a couple of months, if you really want. I don't think waiting is going to change the outcome for the better, especially beyond two or three months. If you want to get a second opinion just for your own piece of mind, do that, but it probably will be the same. Don't go see another doctor just to delay things. Do it because you really think you need to hear it from someone else.

I hope some of this cleared things up, especially about the RAI. Please feel free to write back if you have more questions or just want to discuss things. I wish you all the best.
Did you find this post useful?
|
Avatar
marty217
replied on October 6th, 2009
New User
what size was it and could you have kept the 2nd loeb
Did you find this post useful?
|
Avatar
MyrahU
replied on October 7th, 2009
Active User, very eHealthy
Mine was 1.9 cm, but was minimally invasive with no extension beyond the thyroid capsule.

I talked to my doctor about keeping the second lobe, but there are some problems with that. The chances of recurrence are much higher because they 1. can't give you RAI (because it would damage that second lobe rather than targeting just the remaining cancer cells) 2. the second lobe could get cancer and 3. it would be much more difficult to do follow-up tests to look for cancer re-growth with the second lobe still there. There is this hormone called Thyroglobulin that is secreted by thyroid cells and thyroid cancer cells. It's a simple blood test to check for it (this is when you can have your thyroid stimulated with Thyrogen rather than going off your meds). If the Thyroglobulin gets above a certain level in someone who shouldn't have any at all (ie. someone who has had their thyroid removed and ablated), they know something could be re-growing. If you only have half removed, they can't do that test.

Yes, you may not need thyroid hormone pills if you only have half removed, but some people still need them because the remaining half may not produce enough hormone.

I really think you should seriously consider having all of your thyroid removed (if the first half shows cancer, of course) and having the RAI. I hate to say it, but age really is a factor with these things. After a certain age, chances of survival from thyroid cancer do go down some. They are still really good compared to other cancers, but they aren't the same as they would be if you were under 40 or 50. You need to give yourself the best chance possible to live a full and healthy life.

Let us know what happens. Feel free to re-post with more questions. Smile
Did you find this post useful?
|
Quick Reply
Search