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Extreame bloody nose on advair for emphysema?

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.My mother got a extreme bloody nose just out of the blue, plus she coughed up "chunks" of blood, ive personally never seen a nose bleed that much. She filled up almost 2 cups w/blood and "chunks". does she need to go the a doctor/er immediately or just go to her reg. doctor? she's on chantix for smoking and advair for emphysema.
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