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Womens Health > Endometriosis Forum > Experiences with Lupron?
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Q: Experiences with Lupron?
asked by: katrina911 on October 13th, 2008
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I was recently diagnosed with endometriosis. My gynocologist has suggested that I go through a 3-month dosage of Lupron to see if my symptoms (severe cramping and pelvic pain, increased & painful urination around the time of my period, PMS, etc.) are relieved before we do a laproscopy. I'm set to have the injection at the end of this week.

I know the biggest complaint of Lupron is menopause-like symptoms - vaginal dryness, hot flashes, etc. I'm wondering what I should do to try and alleviate or lessen those side effects, and if there are any other side effects I should know about.

What have been other women's experiences with Lupron? Positive or negative results? Any side effects I should be aware of? Any suggested suppliments/meds to alleviate or lessen side effects?

Thanks ahead of time for advice/answers! Smile
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rooted
replied on October 15th, 2008
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Lupron side effects are listed on the TAP Pharmaceuticals website: http://www.lupron.com/. Most importantly, I think, it the statistic that: "After six months of therapy with Lupron DepotĀ® 3.75 mg, vertebral bone density decreased by an average of 3.2%, compared with the pretreatment value. " More product information here: http://www.endofacts.com/luprondepot/produ ctinfo/

A more comprehensive list of Lupron side effects is on the National Library of Medicine website: http://www.nlm.nih.gov/medlineplus/druginf o/meds/a685040.html

* weakness
* headache
* dizziness
* hot flashes (a sudden wave of mild or intense body heat)
* sweating or night sweats
* tiredness
* nausea
* vomiting
* diarrhea
* constipation
* loss of appetite
* change in weight
* increased need to urinate, especially at night
* breast tenderness or change in breast size in both men and women
* decrease in sexual desire in men and women or ability to perform in men
* decrease in size of testicles
* vaginal discharge, dryness, or itching in women
* absence of menstrual periods in women
* spotting (light vaginal bleeding)
* swelling of the hands, feet, ankles, or lower legs
* depression
* difficulty concentrating
* anxiety or nervousness
* difficulty with memory
* difficulty falling asleep or staying asleep
* flu-like symptoms
* muscle aches
* itching, swelling, burning, stinging, pain, bruising, redness, or development of a sore at injection spot
* firmness or hardness at subcutaneous injection spot
* bleeding, bruising, burning, pain, pressure, itching, swelling, or redness at the place where the implant was inserted
* hair loss
* acne
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Users who thank rooted for this post: katrina911 
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katrina911
replied on November 3rd, 2008
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Well, I had the injection about three weeks ago, and thus far, I'm experiencing some side effects, but none too awful. Have been having hot flashes and night sweats - I'll wake up and be absolutely burning up on minute, and the next minute, I'm freezing. Have also been experiencing headaches and tiredness. I've also been feeling really depressed in the last week.

However, in comparison to the pain I was having with endo every month, these symptoms are not so bad. Smile
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rooted
replied on November 4th, 2008
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Great! I'm glad that it's working for you. Thanks for sharing Smile.
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SexxxyVixxxen
replied on January 20th, 2009
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My experience with Lupron
Hey, I have SEVERE endometriosis and was diagnosed in September 2003, I obtained an AMAZING Gyne and we started the LONG Road of treatments and Pain management. Needless to say I have had 7 Surgery's for Endo and have been on Percocet and Toradol for the intense pain since. I went through countless treatments, and I did try a 6 month cycle of Lupron....well I WILL try to get as many women to STAY FAR AWAY from this drug....I had the worst side effects and my body tok a little over a year to get back to normal. The "False Menopause" was REALLY bad, I had terrible mood swings, depression, weight gain, hot and cold flashes that kept me awake for approx 20 hours out of 24 hours in a day, which then I had to be placed on medications that would help me sleep, I stil had pain and it did NOTHING to help or treat the Endometriosis!!! It was not worth the hassel and upside down life it put me through. I was told to try "Black Cohosh" to ease the "False Menopause" symptoms....did not work for me, but I have heard it works well for most women. Afterwards me and my husband at the time, wanted to actively try and have a baby...like I said it took my body about a year and a half to get back o normal and to start having regular cycles again..after about another year of no luck getting pregnant, I was put on Clomid, I was told that Endometriosis can cause infertility or make it very difficult to concieve on your own.....I did 3 cycles and to my surprise I was diagnosed with Ovarian Cancer, I had my Left Ovary removed in Feb of 2006, I still have my Right Ovary and uterus, and was told that having only one ovary will NOT lessen my chances of having a baby.....I have gotten pregnant 2 times since, but sadly I miscarried both pregnancies....!!

I wish you the best of luck with you battle wih Endometriosis....keep us updated on your experiences with treatment(s)
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Bond004
replied on January 29th, 2009
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Lupron
Yeah the shot hasn't really helped me either. It takes away the pain for a couple days, but thats it. I've gotten the tiredness, mood swings, anxiety, hot flashes, loss of appetite. I just got my 3rd shot and since then I've been having uncontrollable shaking. Last night I couldn't sleep cause of it. I'm not sure what to do about it. I'm scared. I will probably call my doctor today.
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tracylh
replied on February 3rd, 2009
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Lupron - I highly DON'T recommend
I've been on the Lupron shots for 5 months now, biggest mistake I've ever done. I tried to avoid a hysterectomy, but instead I am scheduled for surgery March 11th and my life has been horrible the past few months. Not only am I still in pain, my pain has worsen, to a point there are days that I can't even function. I have a hard time sleeping both from the pain and the night sweats. My bones ache horribly, my body feels and looks swollen. I've gained 10lbs. I'm lossing an incredible amount of hair, my skin is so dry that I've broken out with my psorias, which I haven't had problems with for 10 years. And my face is so broken out, most of the time I just want to cry, it's like my life has been taken from me. I'm on percs and ibrofen all the time and once again today I'm waiting to hear from my doctor because my pain is really unbearable, even with the pain meds. Please do your research before you let them give you this horrible medication, thank God my hubby is so wonderful, because our once healthy sex life has been non-exitence since these shots, I have no desire and when we do I'm just in horrible pain.

Tracy
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Bond004
replied on February 6th, 2009
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Lupron :(
Don't listen to your doctors...they say stuff like I wasn't aware that was a side effect, but they aren't using the product so they don't REALLY know. If you have bad anxiety the shot may intensify it..thats how it was for me. I am also losing hair..it looks like I'm freaking going through chemo. Just take some deep breaths and take it one minute at a time. You have to accept that you have endometriosis even if you may not like it. Don't let it ruin your life!!
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KayPhillips
replied on July 31st, 2009
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I took Lupron, a 3-month shot, and had a great experience with it, so I know it really depends upon the case. I just a few hot flashes and no pain at all-- it was great.
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Users who thank KayPhillips for this post: BRANDYMCNEIL 
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BRANDYMCNEIL
replied on September 27th, 2009
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LUPRON SHOT IS IT JUST TO SHUT U UP CUZ NO HELP.
I had lupron shot last monday and i feel the same amount of pain if not more went to er and have a cyst but my dr. said that isnt painful is something wrong with me he want give me anything for pain......people who have back pain dont have to live with it why do i. and doctor did a lap and said i had endo. so what;s up??i feel like my doctor thinks i am seeking pain meds but i really just want relief. any advice i did the lupron i really can not function in this much pain!!
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Renithia
replied on October 5th, 2009
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Is there any ecision taking by fda against Lupron???
But is there any class action lawsuit against lupron? what the decsion the fda is taking against this drug? I took lupron too it destroyed my happyness in life. I feel like a zombie.
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shellig
replied on October 13th, 2009
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Pain-free?
Lupron seemed to help symptoms in the first month... taking fewer pain pills, etc. with limited side effects (add back hormones were prescribed). 6 weeks in, though, having horrible pain. For those with success, how long before you were pain-free or do you still have to take pain meds?
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