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Elisa repeatedly reactive but western blot was negative?

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Hi, I recently had to take and hiv test for work. My doctor called me to immediatly come in to dicsuss my results. He said my Elisa was repeatedly reactive but my western blot was negative. I am shocked. He referred me to see a special infectious doctor for more testing. I haven\'t been sleeping around and my last sexual encounter was in July and I used a condom that did not break or slip. I then developed jock itch and am taking keconazole for it and it still hasn\'t cleared up. Would that interfere with my elisa test or am I really developing hiv. I see a specialist tomorrow. Western bloc negative. I\'m going crazy


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replied November 5th, 2011
HIV and AIDS Answer A28214
Hello and welcome to e health forum.

Rapid antibody tests are qualitative immunoassays intended for use as a point-of-care test to aid in the ‎diagnosis of ‎HIV infection. These tests should be used in conjunction with the clinical status, history, ‎and risk factors of the ‎person being tested.‎ Also these tests cannot be used as single diagnostic testing ‎methods. These tests should be used in appropriate multi-test algorithms. ‎

Although these tests have high specificity, false positives do occur. Any positive test result should be ‎confirmed by a lab using the western blot.‎

The causes for a false positive results with the HIV ELISA tests include - ‎
Nonspecific reactions, hypergammaglobulinemia, or the presence of antibodies directed to other ‎infectious agents ‎that may be antigenically similar to HIV can produce false positive results. ‎

Autoimmune diseases, such as systemic ‎lupus erythematosus, have also rarely caused false positive ‎results.‎

Since the western blot test is negative, it is more likely that you are HIV negative.

You might get a clear picture, when you consult with the Specialist in infectious diseases, who might be able to clear all your doubts and apprehensions.





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