Hi
Welcome to the forum!
TB blood test is rarely false positive. It detects either a latent infection or an active one. This is done basically to overcome the false positive or false negative result of TB skin test. You would be taking the skin test too so if this too is positive then TB is confirmed.
Regarding ANA being positive: only 20% patients with discoid lupus are ANA positive, so it is not a major diagnostic criteria. Biopsy was confirmatory in your case.
In discoid lupus patients with negative ANA, the possibility of another systemic illness like tuberculosis should be suspected, especially if there are other symptoms apart from skin lesions, as mentioned by you (symptoms for SLE and heart, and lung problems). If at all you have TB then you will have to take treatment for the same. It is possible to treat both together.
Hope this helps. Take care!
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