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Study done in animals have shown that the Fluconazole use (chronic use) can affect the serum testosterone levels, semen volume, count and percentage of motile sperms. If in doubt, consider getting a complete semen analysis done. If you have been trying for pregnancy (for more than a year) and have not been successful, you should consider getting a complete infertility work-up done for you and your partner to see if there are any underlying causes for the infertility/inability to conceive. Treatment as needed (based on examination and investigations results) would be started to help her get pregnant. Have diet with foods rich in zinc content to ensure better maturation of egg and sperms. Your partner should monitor cervical mucus changes and the BBT (basal body temperature) charting to predict ovulation and time the intercourse for having fruitful results. Have intercourse in positions that allow for deeper penetration for high deposit of semen. She should be in regular monitoring and follow-up with her treating doctor/gynecologist and report any new/abnormal symptoms immediately.
Take care.