I am a 34 year old (otherwise healthy) female who has been suffering from a chronic YI--symptoms do not ever subside--for a number of years now. I have been to numerous gynecologists and one infectious disease specialist for this condition and the only thing that has EVER successfully treated it was Diflucan--and I'm not talking about the standard "one pill" treatment or even the "one pill a week" treatment either. I'm talking about one pill EVERY DAY for a month straight. The infectious disease specialist gave me a prescription for that and it was the ONLY time my symptoms disappeared. The YI did come back shortly after I stopped taking the medicine and when I went back to the doctor she simply said there was nothing else she could do for me. That's basically what I've been told by all the gynecologists too--that they've tried everything and that the only thing I can do for myself now is to change my diet.

Presently, I am beginning a very strict YI diet (no sugar, no yeast, no alcohol, etc.) and have ordered a month's supply of generic Diflucan through an online pharmacy (no script required). As before, I will be taking 200 mgs. per day. I am hoping that this, in conjunction with my modified diet, will be enough to rid my system of the persistent YI. My question is, has anyone else had any experience with taking such a high dosage of Diflucan? I know that it is associated with the risk of hepatoxicity (chemical-driven liver damage) in certain individuals, and that in some cases a doctor should monitor your liver function while you're on it, but the infectious disease specialist I saw did NOT do that. She just wrote the prescription and I was out the door.

If there are any medical experts out there who could shed some light on this issue, I'd really appreciate it. I know that it is unwise to self-treat with a medication that should only be prescribed by a doctor. Believe me, I do. But at this point I am up against a brick wall. I want to be healthy and I want to be free from this condition for good. It is literally ruining my life.

P.S. Other than antihistamine medication (which can decrease the effectiveness of Diflucan) I am not currently taking any drugs which may interact with fluconazole. I do not have liver disease and as far as I know the only thing that might put me at risk for hepatoxicity while using Diflucan is my past history of moderate alcohol consumption.