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Conditions and Diseases > TMJ Forum > Diclofenac for pain, inflamation
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Q: Diclofenac for pain, inflamation
asked by: edgaras on June 13th, 2008
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I know one member has tried this medication and reported good results.
I wonder if anyone else tried it, if so, please share you experience. This medication is, I qoute, "Topical diclofenac produce[s] maximum concentrations in plasma of 4-80 ng/mL after single or multiple applications (Table 1). Also, "concentrations of NSAID in tissue, particularly meniscus and cartilage, were very much higher after topical than oral administration, indicating that direct absorption through the skin into tissues of the joint does occur." I believe Diclofenac is available as topical patch in UK and Australia, but not in the USA. Mad

"Synovial fluid concentrations of NSAIDs after topical application were generally lower than those found in plasma."

And again, "Synovial fluid concentrations are also lower, but concentrations in meniscus or cartilage are 4-7 times higher than after oral administration.

I hope and pray that future development of topical medications becomes available in the US.






References:

J Radermacher et al. Diclofenac concentrations in synovial fluid and plasma after cutaneous application in inflammatory and degenerative joint disease. British Journal of Clinical Pharmacology 1991 31: 537-541.

http://www.jr2.ox.ac.uk/bandolier/booth/pa inpag/topical/topkin.html

Ideas:


Let's move to UK/Australia? For one, they have national health insurance,
no limits on TMJ coverage, etc. Perhaps topical medication is available online.
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TMJWorld
replied on June 13th, 2008
Extremely eHealthy
there is a topical medication that i have used in the past---its a pain releiver and antiinflamitory---its called ketoprophen--im not sure what the avalibility is.


Moving is not always the practical way to deal with health coverage denial
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edgaras
replied on June 26th, 2008
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Gel
It turns out, that there is a gel, diclofenac gel, avaiable in US, with price tag of about $400. I finally got insurance, with insurance it cost me $60. One application contains about 30 mg of the medication, and is supposed to go into the skin, so subdermal (under the skin) absorbtion is likely to be minimal, but I decided to give it a try. I am also taking 50 mg of diclofenac orally, which seems to help with the pain, and I feel that the joint is not as inflamed, although pain is not completely gone, so that's why I am trying to this gel.

As far as another country, seriously, I have considered it, especially when thinking about the cost of arthroscopic surgery, if it is necessary, I am avoiding it, and not sure if insurance will cover it.
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msyoga
replied on June 26th, 2008
New User
hello, i myself taken diclofenac for chronic back pain due to arthritis. Well i was on this med for 2 months, i didnt' feel any relief, but i notice i started to get bladder infections and kidney started to act up, so i quit. i still have full bottle. but i was wondering if the topical would be better for me to use. I'm tyring to avoid getting epidural shots for my back, but it's been 6 months for me constant pain. any suggestions.
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TMJWorld
replied on June 26th, 2008
Extremely eHealthy
well--surgery is the last option---tmd isnt coverd by insurances so it wont cover it. and there are plenty of options there for you to try first
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edgaras
replied on June 27th, 2008
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I am not sure if you remember, but I have talked about wearing orthotic device (splint). Two types, one for night, one for day, nightly one is the only one which appears to help, without it, pain returns and is incapacitating.
I have undergone physical therapy, I will try one more attempt with a specialist who particularly specializes in this area. I have tried .. I have.
Accupuncture too.


I hope, insurance will cover this, given that they state that certain services, related to excision of jaw cysts is covered. Otherwise, I will leave USA for good, perhaps UK. It is silly indeed how people are abused by the way the system is set up. If anyone wants to know more about how people are treated in other countries, who are not on the bottom of the WHO list of
countries rated for health.

Capitalism at it's best - when people die when insurance denies coverages, it's a shame how congress can be bought by insurance agencies and do nothing in the eyes of God for all these years.
Even autism related services is not covered here in Illinois, and although the bill who will mandate the coverage has passed the house, it is sitting in the appropriations committee - reason? I suppose the lobbying.

Good film about the health systems around the world, that I recommend for people who are over 30, and are brainwashed to believe that "that would be socialism, and there would be lines to see doctors", I would recommend to see "Sick around the world", a documentary by PBS.
It has been recently part of presentation shown at Senate Finance Committee 2008 Health Reform Summit, which can be seen in full for free at http://38.105.88.161/Search/basic.asp?Resu ltStart=1&ResultCount=10&BasicQuer yText=sick\ around the world .

Reform is needed, many a suffering, Is anybody listening?
I used to work for a collection agency, collecting medical bills,
there were families, families that do not make enough money, being sued for medical bills. I left the company and now understand much of how "the system works".
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mandibular_mess
replied on June 24th, 2009
New User
I have tmj. My doctor gave me 2 sample bottles of voltaren gel (diclofenac sodium topigal gel) 1% for a pulled muscle in my back. I tried applying to treat my tmj and it did nothing at all. If you want to try for yourself, it's best to try and get a free sample.
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