Depression Forum - Switching from Prozac to a New Drug

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Q: Switching from Prozac to a New Drug

asked by: DoctorQuestion on March 3rd, 2008

I have been prescribed 40mg of Prozac for the past two years but, due to the side effects, my doctor is considering changing to a new generation anti-depressent NSRI which firstly affects neurodrenaline. I am concerned about the 'switching' period because Prozac has such a long half-life. I am also concerned about seretonin sydrome. Can NSRIs be introduced while SSRIs are still int he system?

Replies(1)

Dr. Nikola Gjuzelov , MD

replied on March 15th, 2008

Depression Answer A3796

Seretonin Syndrome typically occurs only in patients who are over-dosed with an SSRI medication. Switching from Prozac to an NSRI drug does not have this effect.

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