Hope your doing well.I am kind of confused regarding testing for syphilis since i might have been infected 12 years back. I have swollen nodes in the neck region, and i have a canker like circular scar on the skin of my penis( could this be a mark left after the canker heals? ). Recently i even noticed a few blisters on the foreskin and I have 2 fibrous growth under the skin one on my inner thigh and another on my chest (< 1 cm diameter). I read sometimes tests for syphilis are not very accurate in late stage of the infection. I did a Treponema pallidum haemagglutination and a VDRL test which were negative. Now my confusion is, have i already progressed into a late stage like neurosyphilis and is a CSF test required? Is there a way i can conclude i am not infected with syphilis?
I will be happy if you can help me by sharing your view on my problem. I want to act quickly to avoid any further health complication.
The Treponema pallidum particle agglutination assay (TPPA) and Fluorescent treponemal antibody absorption (FTA-ABS) test if positive are diagnostic of syphilis. Since TPPA is negative, FTA-ABS can be done to confirm diagnosis. Both the tests can be sued to diagnose any stage of syphilis except the first 3-4 weeks when they are negative as sufficient antibodies have not formed.
Penile ulcers may be due to infective or non-infective causes. Infective causes are sexually transmitted and include syphilis, gonorrhea, chancroid, genital herpes, LGV and granuloma inguinale. Hence all these should also be tested for. Since a confirmed diagnosis cannot be given on net please consult your urologis/venerologist to find the cause. Hope this helps. Take care!
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