CML -after starting Tasigna in excruciating pain

Hello and thank you for posting your medical question on E health forum.

From the description here, it seems that there might be a progression of the CML to blast crisis, resulting in increase in the severity of the symptoms.

This could also be a indicator of failure of therapy.

But the definitive diagnosis will be made by a physical examination and diagnostic evaluation.

You might consider consulting your hematologist for proper treatment.

I hope this helps.