Clozapine & Low White Blood Cell Count Posted: 05-12-08 21:41pm
Hi
My 16 year old has been recently diagnosed
with schizophrenia and has been extremely
ill since November although she is
improving slowly now.
She is on a cocktail of drugs including
clozapine which worked very well when
first introduced and she seemed to almost
make a miraculous recovery.
At about 9 weeks into the clozapine
treatment she was up to 300mg/day when her
WBC and Neutrophil count dropped into the
red zone.
After coming off the clozapine as required
by Australian protocols she then
recommenced treatment with very slow
increases back up to 75mg/day where she
has remained for several months due to her
WBC and Neutrophil count remaining in the
Amber zone.
This dosage appears to be holding her
stable but not enabling further progress
(she continues to experience psychosis).
I would be appreciative of any suggestions
or information anyone has to offer
regarding known strategies for increasing
the WBC and Neutrophil count.
The only thing that has been tried so far
is the introduction of Lithium and the
cessation of several ancillary
medications, none of which appears to be
working.
I would also be interested in hearing
about anyone who has had a similar
experience and what outcome was achieved.
Regards
PC5149
|
CarolDiane
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Posted: 06-25-08 05:45am
I was changed from Lithium to Depekote ans
Seroquil and doing fine now. I an allergic
to Lithuim. Bipolar meds are notorious for
lowering your WBC from what I have heard.
I have my labs done again in three weeks.
Last time on Lithium it was just slightly
low. But I have a low immune system anyway
and can not afford to go to much lower. I
really don't think there is anyway to up
the level other then IV infusion.
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