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Conditions and Diseases > High Blood Pressure and Hypertension Forum > Cholesterol and treatment medications
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Q: Cholesterol and treatment medications
asked by: DoctorQuestion on March 26th, 2008
I am 38 Years old. I hace Elevated Total Cholestrol, Tryglyceride ,LDL and Uric acid since 2003. I changed my food stlyle and doing Exrcise as time permits.The levels TC and others came to border line. After some time again it will go up. Recently I took Tonnac for one month , then tested Everything is normal except SGOT and SGPT . They incresed above 100 and Doctor told me stop the medicene. Then started EZENTIA. After 2 months again I tested my blood. Results are TG is 730, TC 238, HDL 40, LDL 50 and Uric acid 383 and all oters like sugar , sgot , sgpt are normal. That measns TRiglyceride is very high. I never had this much. So please advice me what type of medicine ishould take? Because all these LIPI... medicine will affect my liver. How can I reduce my TC and TG by exercise and diet.


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Dr. Nikola Gjuzelov , MD
replied on April 8th, 2008
High Blood Pressure, Hypertension, High Cholesterol Answer A3898


When both cholesterol and triglycerides are elevated, the medicine of choice is from the group of statines (simvastatine, pravastatin, lovastatin…). If triglycerides are above 4,5 mmol/L a combination of some statin and some fibrate (gemfibrozyl, fenofibrate, bezafibrate) is used. Unfortunately both of these groups of medicines (statines and fibrates) can cause liver damage.


Other medicines for treating the increased blood fats are:
1. Rezines (cholestiramin and cholestipol) – they don’t affect the liver but act only on total cholesterol (TC) and LDL;
2. Guar-gum - it doesn’t affect the liver but acts only on the TC and LDL;
3. Ezetimb (Ezentia) - prevents absorption of the cholesterol in the intestines. Acts on both cholesterol and triglycerides. It does not affect the liver.


Diet and physical activities are absolutely necessary and are the first step in treating such disorders. You should also check if you have diabetes or hypothyroidism because they can also cause increased blood fats.


You may want to consult an endocrinologist about your case.





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