I have been on Suboxone for a little over 3 years now and have been taking Chantix for a week and a half. Actually came across this post looking for more answers. The only problems I have had are the stomach sickness(nausea). And I find that breaking the dose down from 2 (1mg) pills per day to 4 pills per day (cut in half so .05 mg) along with eating about 30-60 minutes before my dose keeps that at bay. I do think that Chantix is effecting my Suboxone. But not in a bad way. I have been on 21 mg per day and really want to stop but so far have not had the will to go through the withdrawals and i have tried several times. It's not that they are very bad, it just takes a while for the Subox to be out of your system. I tested today to see if it effects me and have not taken any Suboxone yet where I normally would have had my second dose by now and I feel fine. I am no Doctor and everyone is different but I think both drugs are good compared to the alternatives. And I could be wrong about it effecting Suboxone. I am just hoping I am not so I can stop both. My Doc says he has had great success with the patients who have tried Chantix to quit smoking. These are all patients who probably take Suboxone. I do have vivid dreams but nothing scary, just detailed. I actually enjoy that side effect. If you do end up taking it drink allot of fluid before your dose. Let your food somewhat digest, keep candy or gum, crackers, ginger ale, anything that will help you with the nausea and the smoking itself. Chantix is working because I can't stand to smell smoke anymore. Smoking has become gross, even some foods taste horrid. If you really want to quit it helps tremendously.