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chances hiv negative at 90 days become positive?

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what are the chances of a hiv negative person at 90 days become positive at 6 month? for a low rish exposure does that ever happen ? i am aware of the late seroconverters with predisposing medical conditions take longer time to seroconvert apart from such people ,do normal people need to be worried of such a senario ??


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replied May 5th, 2011
HIV and AIDS Answer A22648
Hello and welcome to E health forum.

HIV antibody tests in a normal individuals - should be done atleast after 4-12 weeks of exposure. (Antibodies to HIV are produced by 4 weeks in 90% individuals who had a infective exposure and a positive test result). The test result at the end of 12 weeks can be considered conclusive. (This is to clear any remaining doubts).

It is extremely rare for a NORMAL person to take any longer then 6 months to develop detectable antibodies.

Conditions that result in late production of antibodies are rare genetic diseases - and do present much earlier in life and individuals will always be sick with respiratory and diarrheal infections throughout their life.

Such disorders include :

1. Disorders of antibody production: Hypogammaglobulinemia ; X-linked agammaglobulinemia ; IgA deficiency ; IgG deficiency ; IgM deficiency ; Hyper IgM syndrome ; Wiskott-Aldrich syndrome • Hyper-IgE syndrome

2. Common variable immunodeficiency

3. Cell-mediated (T) : Di George's syndrome ; Purine nucleoside phosphorylase deficiency
Severe combined (B+T) x-linked: X-SCID ; Adenosine deaminase deficiency

4. Conditions resulting in : Leukopenia, Lymphocytopenia , Idiopathic CD4+ lymphocytopenia

5. Complement deficiency

It is in such individuals, that testing after 12 weeks or after 6 months is advised.

I hope this helps.



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