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Certain HIV positive, but negative tests (Page 54)

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October 29th, 2012
Experienced User
I think it is good that everyone look for possible diseases. For myself I am going to check for mycoplasma fermentans later this week. This is a virus which could cause all these symptoms as well.

As for HTLv, I still think there is a possibility of it, or it could be XMRV < AGREED WITH TONY>. Let us test for different possibilities to see which one comes back positive!
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replied October 29th, 2012
Extremely eHealthy
Hope,

Thank you for your support - like I said, let's be scientific and test for everything PROPERLY. I'd love for this to be something that we can all test for and (God willing) be cured of. But in the event that isn't the case, we need to deal with it nonetheless. If you guys are serious about ruling out HTLV, then we need to follow the Brazilian protocol and get BOTH Western Blot / Line Immunoassay testing, along with PCR testing, and not just get the antibody test.

D-man,

I appreciate your efforts to prove that we have a bad Staph infection, along with Hope's mycoplasma theory. But you have the keep in mind that retroviruses (HTLV, MLV, XMRV, and HIV) suppress the immune system, which leaves the patient vulnerable to infections, especially those involving the skin and mucosal areas. So a retrovirally infected patient could easily get your Staph infection, or DFrank's Candida infection - I've had both, and thank God they were treatable and have gone away. But am I okay now? Of course not - I'm still in considerable pain, but the Staph and Candida have not returned (and hopefully never will), still I am not well.

A Western Blot / Line Immunoassay test will show which proteins of HTLV can be detected in our blood, P24 is one which is shared by HIV, others include P19, etc. If you guys don't want to take the test because you're afraid of having a protein that's shared by HIV, I completely understand. For those people (and everyone else), contact Pfizer Pharmaceuticals and ask for a week's dosage of Tofacitinib, it's a tiny 5 mg tablet that you take twice a day. If the Tofacitinib makes you feel better, then at least I've given you a path away from your suffering. Will Tofacitinib cure HTLV, MLV, XMRV? I don't know - either it will suppress the virus enough that we can lead normal lives, or (GOD WILLING) it will eradicate the virus from our bodies after long term dosing. Only time will tell my friends.

Best wishes.
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replied October 31st, 2012
Experienced User
Has anybody on this forum tested for TRICHMONIASIS??
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replied November 7th, 2012
Extremely eHealthy
Xeljanz / Tofacitinib as a treatment for HTLV
TODAY Pfizer says the Food and Drug Administration approved its rheumatoid arthritis pill Xeljanz (ZEL'jans), seen as potential big seller for the world's largest pharmaceutical company.

Pfizer Inc. says the FDA approved Xeljanz as a treatment for moderate to severe rheumatoid arthritis in patients who can't take methotrexate or haven't been helped by it. Xeljanz is intended to slow the progression of the disease. The approval comes about two weeks sooner than expected.

Xeljanz, or tofacitinib, is the first rheumatoid arthritis treatment from a new class of pain medications called JAK inhibitors. The drugs interfere with enzymes that contribute to tissue inflammation.

Rheumatoid arthritis is a major area of research for drug companies because it is a chronic condition, meaning patients will likely take the drugs regularly for a long time.

NOTE TO EVERYONE WHO IS SICK ON THIS FORUM:

I am strongly recommending that you try this medication for ONE WEEK. I have anecdotal reports that people are experiencing improvements after a FEW DAYS. If we all try this for one week, and if we all feel better, then we will have made MAJOR PROGRESS.

Best wishes.
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replied November 9th, 2012
Experienced User
are you trying?
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replied November 9th, 2012
Extremely eHealthy
Not yet, but will be before the year ends.
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replied November 8th, 2012
More than five months of tongue issues
Hello everyone,

I am interested in your stories because I have some weird symptoms for the past months:

white tongue
hyper salivation
irritated taste buds in the tip of the tongue
teeth marks in the tongue's border

All these symptoms came 4 months after a one night stand with a girl (unprotected oral sex from her to me, the rest protected). I am currently living with these symptoms FOR THE LAST FIVE MONTHS.

My white tongue is not thick, and it usually goes away after I eat something, then comes back some hours later. The irritated taste buds are the problem. When I speak too much, the friction between the tip of my tongue and teeths is sometimes uncomfortable/painful.

Has anyone similar symptoms like mine's?

Some pics of my tongue:

Tongue left side: notice the pimple/irritated taste buds
http://imageshack.us/f/825/tongueside1.jpg /

Tongue front: notice the irritated taste buds
http://imageshack.us/a/img687/6173/tonguef ront.jpg

The picture below is not mine, but it looks like my tongue:

http://www.tcmyellowpage.com/Literature/Up loadPic/2012-8/201281421352639901.jpg

About the tests, I have been tested negative for HIV, Vironostika Uniform Ag/Ab at 5 weeks, 2 months, 4 months, 7 months, and then with a CMIA Ag/Ab (I think it's an Architect Abott test) at nearly 9 months post exposure.

I still didn't do a PCR RNA and a CD4 count. My WBC is low, at around 4,5 (range from 4 to 10).

I have been tested positive for CMV, Herpes (don't know if 1 or 2), Hepatitis A and EBV.

A tongue culture revealed yeast 4 months post exposure. However, I have been tested for it twice in the last 2 months and it came back negative. There were also some bacterias found and some were erradicated, however, I still have this bacteria: Haemophilus influenzae. The doctor didn't want to give me more antibiotics because she does not think this is the reason of my tongue problems.

So my doctor (a dermatologist) recommended me to go to an inmunologist, and maybe also to an oral surgeon, to take a biopsy of these pimples/swollen taste buds on my tongue.

I will keep you posted if I ever find the solution to this. I would also be interested if someone had similar symptoms. I have not found many people with these symptoms so far.
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replied November 9th, 2012
Experienced User
tested for htlv/ mycoplasma fermentans yet?
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replied November 9th, 2012
Experienced User
tony, do you mean there are patients with htlv positive tested the drug and find it effective?

how about anyone tested negative but suspected htlv tested the drug?
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replied November 9th, 2012
Extremely eHealthy
Hope,

I mean that medical research has shown that XelJanz (tofacitinib) reduces HTLV in test tube studies. Being that it is a JAK (Janus Kinase) inhibitor, it reduces inflammation, and since inflammation feeds HTLV, reducing inflammation reduces HTLV. The Face Book page for HTLVhelp shows diagrams that explains how JAK inhibitors interrupt the HTLV lifecycle, along with IKK inhibitors (BMS-345541) & CDK inhibitors (Purvalanol-A). So theoretically, a powerful HTLV "triple cocktail" would consist of inhibitors of JAK and IKK and CDK.

Best wishes.
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replied November 11th, 2012
Experienced User
thanks tony.

recently, I am suffering great pain in the whole body. calf keeps smallen and vision gets more blur and blur.

I am getting more and more intolerable to heat. I am really afraid.
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replied November 12th, 2012
Extremely eHealthy
Hope,

We are both going through the same thing; just like you, my body is in pain and like you I am experiencing muscle wasting, and like you I am experiencing vision blur worse & worse. You need to work on your intolerance to heat, since the virus looks to reduce temperature to replicate. Higher temperatures kill viruses, so consider taking very hot baths, sleeping with a heating pad, and wearing warm clothes.

Best wishes.
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replied November 12th, 2012
Hi guys any update, after 10 month HIV test negative but CBC is not normal my white blood count 11.48 higher and platelet r high then limit to its 542 and limit is up to 500, htlv 1/2 PCR were negative after 8 month with antibody test for htlv too.
Tony did u tested again? Or any other member plz share me your results.
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replied November 12th, 2012
Extremely eHealthy
One,

I'm glad that you are seriously pursuing testing - high WBC and high platelets are both signs of HTLV infection. I appreciate that you are doing both PCR & antibody testing for HTLV. So far I have tested negative on 4 HTLV antibody tests, and one PCR test, and am going for another HTLV test next week.

Best wishes.
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replied November 13th, 2012
Extremely eHealthy
Another forum
In case this thread eventually gets shut down, I wanted you all to know that there's a great forum on forums dot phoenixrising dot me - many people there are very knowledgeable about HTLV, MLV, and XMRV.

Best wishes.
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replied November 14th, 2012
Experienced User
I would rather think this is a new pathogen rather than HTLV. (Due to the fact that many people getting negative all the time) Do you ever thought of getting your blood for investigating new stuff?
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replied November 14th, 2012
Extremely eHealthy
Hope,

I've been tested for everything, to the total of ten thousand dollars. Believe me, it is HTLV, all of the symptoms fit, and Sowadsky on TheBody site said that it can take years to show up positive for HTLV. The logical thing to do at this point is to try the recently approved Xeljanz pill for a week - if that makes you feel better than that proves it's HTLV. Anyone else on this forum is free to suggest another ailment and a cure, but right now HTLV and Xeljanz are our best guess; other people on this forum agree.

Best wishes.
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replied November 14th, 2012
Hi everyone, specially tony did u had full blood counts recently ? Do u guys did cd4 cd8 counts? As doctors say that if you have symptoms your test should be positive, so if we have symptoms from htlv so test should not positive? What you guys think, tony when was ur last test? Is there any one tested more then a year but still worried? If PCR test even can not find the virus up to 7.5 month what is use of PCR test? What is the end point? Even htlv dr examin me at 7.5 month and said I am fine I am out of window period, but now after 10.5 month y my WBC gone too high? Why my platelet are too high and increase 100 with in only a month? Which test now I do after 10.5 month? What symptoms you guys still have? Do you still have lower back pain or its gone away?, I have only 2 year son, God bless you all.
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replied November 14th, 2012
Extremely eHealthy
One,

I agree that HTLV testing is frustrating to say the least - your 7.5 month testing should be sufficient for ANY disease. And yes, doctors believe that HTLV testing is conclusive, but it's not. The best article on this topic describes the Brazilian protocol for testing (recall that Brazil has a serious HTLV problem). In that protocol, the patient is tested THREE ways:

(1) HTLV antibody.
(2) HTLV PCR.
(3) HTLV Western Blot / Line Immunoassay.

Obviously the reason for this triple testing approach is that HTLV has evaded testing. Personally, I've had HTLV antibody & PCR testing done, those were negative. So to answer your question about which test to do next, our only option is the Western Blot / Line Immunoassay test. This test should detect proteins of the virus (p24, p19, p15, etc). I'm asking everyone on this forum to take this test.

Best wishes.
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replied November 14th, 2012
Ok so I m going to do western bolt now, but I read on lab details it not much sensitive as other antibody test for htlv, and even htlv clinic dr in uk told me, PCR and western bolt are less sensetive then antibody test, any ways I will go for that too, but tell me if I am getting symptom with any virus from 7-8 months I should have antibody up to know if not so PCR test should find virus after seven months and after symptoms of 6.5 month or not? If my western bolt come back negative so where I should end up, plz pray for me I am already with abnormal blood results, God bless us all.
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replied November 14th, 2012
Extremely eHealthy
One,

We're all in the same boat, we're all suffering, and we'd all like answers to what's wrong with us. The Western Blot / Line Immunoassay is used a confirmatory test. What's the name of your doctor? I've been corresponding with Dr. Joe Zunt. God bless us all indeed.

Best wishes.
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replied November 15th, 2012
Experienced User
htlv
Is this the test you talking about tony.

INNO-LIA HTLV I/II Score

Finally, a clear answer in HTLV confirmation.

INNO-LIA HTLV I/II Score is a line immunoassay for confirmation and discrimination of human T-cell lymphotrophic virus type I (HTLV I) and type II (HTLV II) infections.

Article number: 80541 (20T - CE)

Features & Benefits

* Complete answer in one test:
o Confirmation and discrimination in one assay
* Lowest follow-up rate:
o Lowest rate of indeterminates
o Optimal specificity in screened-negative blood donors: 99,7% (304/305)
o Optimal sensitivity for HTLV I (100%; 218/218) and HTLV II (100%; 112/112)
*
Low chance of errors and limited hands-on time
o
Color-coded reagents
o
Ready-to-use reagents
o
Fully automated processing of the strips possible using Auto-LIA 48, Auto-LIPA 48 and AutoBlot 3000H.
o
Objective, automated reading and interpretation of strips possible using LiRAS for Infectious Diseases


Strip design



INNO-LIA HTLV I/II Score

INNO-LIA HTLV I/II Score is a line immunoassay to confirm the presence of antibodies to human T-cell lymphotropic virus type I (HTLV I) and type II (HTLV II) in human serum or plasma. The assay also differentiates between HTLV I and HTLV II infections.

The assay uses well-defined antigens derived from HTLV I and HTLV II immunodominant proteins. The antigens are either recombinant proteins or synthetic peptides that are purified and fixed on a nylon membrane. The antigenicity exhibited by these proteins and peptides is either common to HTLV I and HTLV II antibodies or type-specific to one of the two viruses allowing confirmation and discrimination in a single assay. Two gag bands (p19 I/II, p24 I/II) and two env (gp46 I/II, gp21 I/II) bands are applied as non-type-specific antigens, used to confirm the presence of antibodies against HTLV I/II. The type-specific antigens (gag p19-I, env gp46-I) specific for HTLV I and (env gp46-II) specific for HTLV II, enable differentiation of HTLV I and HTLV II infections. In addition, the strip includes one streptavidin control line, two control lines (human IgG), and one strong positive control line (anti-human IgG), which also serves as a sample addition control line.

Documentation



Click here to download the product leaflet as PDF
Publications

* Human T cell leukemia virus type I (HTLV-I) and human diseases.
* Assessment of a new immunoassay for serological confirmation and discrimination of human T-cell lymphotropic virus infections.
* Comparative performances of enzyme-linked immunosorbent, Western blot, and polymerase chain reaction assays for human T-lymphotropic virus type II infection that is endemic among Indians of the Gran Chaco region of South America.
* Evaluation of the INNO-LIA HTLV I/II assay for confirmation of human T-cell leukaemia virus-reactive sera in blood bank donations.
* Confirmation and discrimination of HTLV-1 and HTLV-2 antibodies using a line immunoassay (LIA-HTLV).

Background

Human T-cell lymphotropic viruses type I and II (HTLV I and HTLV II) are related exogenous human retroviruses. HTLV I was first isolated in 1980 from a patient with cutaneous T-cell lymphoma and, in 1982, HTLV II was identified in a patient with hairy cell leukaemia.

HTLV I has mainly been etiologically linked with a lymphoproliferative disease known as adult T-cell leukaemia (AT), a chronic myelopathy known as tropical spastic paraparesis (TSP), and also with other inflammatory conditions. HTLV II infections have not so far been associated with any type of leukaemia or other disease. Most HTLV II-infected individuals remain completely asymptomatic. The virus is transmitted from mother to child, by blood transfusion, and via sexual contact.

HTLV is endemic in Central and West Africa, the Caribbean, and parts of South America, Japan, and Melanesia/Australia.
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replied November 15th, 2012
Extremely eHealthy
AdviseMe,

Yes, that's exactly what I am talking about, thank you!

Best wishes.
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