If you have psychosis or a tendency to schizophrenia, definitely marijuana should be abstained from, as well as alcohol, caffeine and other drugs. Interestingly, even smoking cigarettes reduces oxygen in the brain and contributes towards brain damage. Perhaps this is why so many smokers have schizophrenia. My daughters mental condition always radically improves when she quits smoking cigarettes.
Regards the brains of schizophrenics, elsewhere I was led to believe brain scan abnormalities shown are a result of prescribed antipsychotic use. Without drugs, the brain of a schizophrenic is normal.