can dayquil or nyquil lower the effectiveness?

Hi there. I have a few questions. I am on Tri-Sprintec. I have been on the pill for roughly 4 years now and have pretty good knowledge as is. My first question though is can dayquil or nyquil lower the effectiveness of my pill? I have tried looking this up and my doctor's office is hard to reach sometimes. I've gotten different answers seeing as how it's just the internet. My second question is something I heard, and also tried researching. Will grapefruit lower the effectiveness of the pill? I love grapefruit, but ever since I heard that, I have steered away from eating it. My last question pertains to my period. Ever since I started the pill 4 years ago, I've always gotten my period on a wednesday into my inactive pills. Over the last few months, my period has been actually coming sooner than that wednesday (tuesdays and mondays). Is this normal? Thank you so much for your time!