If you don't take your medications like you are supposed to, then they aren't going to work. You are nuts to begin with because you were smoking drugs and that's what made you have the artificial feeling you did....the bad part about smoking stuff is that there is always a time when you are going to come down off it and it's never nice to feel the normalities of life, so you have to keep doing it and become addicted. Not only that, you've lost friends too.
You should mention your drug usage to your doctor to make sure there are no harmful side effects for smoking and taking your meds at the same time. All in all, you need to drop the smoking.
If you post in the addiction recovery section, I'm sure there will be people there to help you out with this as well.